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The natural history of late‐onset epilepsy secondary to vascular disease
Author(s) -
Fish D. R.,
Miller D. H.,
Roberts R. C.,
Blackie J. D.,
Gilliatt R. W.
Publication year - 1989
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1989.tb03921.x
Subject(s) - epilepsy , medicine , stroke (engine) , occult , natural history , cerebral infarction , central nervous system disease , pediatrics , infarction , vascular disease , surgery , cardiology , myocardial infarction , ischemia , psychiatry , pathology , mechanical engineering , alternative medicine , engineering
Twenty‐nine patients with late‐onset epilepsy were followed prospec‐tively for a mean period of 4.9 years; 14 had CT evidence of occult cerebral infarction and 15 had normal scans. The prognosis was similar in the 2 groups; 57% and 53% respectively became seizure‐free. One patient in each group had a myocardial infarction and one patient with occult cerebrovascular disease had a stroke. A separate study was made of the prognosis of 24 patients with epilepsy following stroke (mean follow‐up 5.9 years). Twelve of 12 patients with seizure onset within 2 weeks of the stroke became seizure‐free, compared with 7/12 with more deiayed onset. Late‐onset epilepsy has a favourable prognosis, and excellent control should be expected if seizures commence within 2 weeks of stroke.