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Erythrocyte fatty acids in multiple sclerosis
Author(s) -
Evans P.,
Dodd G.
Publication year - 1989
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1989.tb03917.x
Subject(s) - polyunsaturated fatty acid , multiple sclerosis , sphingomyelin , concomitant , medicine , cholesterol , chemistry , biochemistry , fatty acid , endocrinology , biology , immunology
Analysis of the fatty acids in the erythrocyte lipid of multiple sclerosis patients in Italy gave no indication of any difference in composition compared with that of a healthy control group. Supplementation of the diet of another group of similar patients with polyunsaturated fatty acids led to increases in the erythrocyte levels of linoleate and docosahexaenoate, with concomitant falls in oleate and elaidate. Levels of fatty acids such as lignocerate and nervonate that are found predominantly in sphingomyelin were similar in all 3 groups.