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Conduction velocity study in type 1 diabetic patients
Author(s) -
Meli F.,
Cardella F.,
Raimondo D.,
Modica A.,
Muscarella A.,
Fierro B.
Publication year - 1989
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1989.tb03905.x
Subject(s) - nerve conduction velocity , medicine , sensory nerve , sensory system , diabetic neuropathy , diabetes mellitus , peripheral neuropathy , cardiology , nerve conduction , peripheral , hemoglobin , latency (audio) , insulin , motor nerve , anesthesia , endocrinology , anatomy , neuroscience , psychology , engineering , electrical engineering
— The role of metabolic abnormalities in the development of diabetic neuropathy is controversial. To investigate the peripheral nerve function and the influence of hyperglycemia on nerve conduction in insulin‐dependent diabetes, a one‐year neurophysiological study was carried out in 30 type 1 diabetic patients ranging in age from 2–16 years. During the 12‐month follow‐up period the glycosylated hemoglobin determination, motor conduction velocity of the peroneal nerve and the motor and sensory conduction of the tibial nerve were assessed 3 times, at the beginning of the study and every 6 months thereafter. The sensory latency was found significantly delayed in these patients as compared with the controls. The degree of sensory conduction slowing correlated well with the glycosylated hemoglobin concentrations and improved with the reduction in hyperglycemia.