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Acetylcholine receptor antibody in myasthenia gravis
Author(s) -
Marchiori P. E.,
Reis M.,
Quevedo M. E.,
Scaff M.,
Cossermelli W.,
Assis J. L.,
Oliveira R. M.
Publication year - 1989
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1989.tb03898.x
Subject(s) - myasthenia gravis , radioimmunoassay , acetylcholine receptor , acetylcholine , pathological , medicine , antibody , receptor , endocrinology , immunology
— Radioimmunoassay techniques were used to detect antibodies to the acetylcholine receptor (AAChR) in 164 patients with adult‐onset myasthenia gravis. AAChR levels above 0.6 nM/l were considered pathological and were found in 67% of the patients with an average value of 58.99±125.02 nM/l (0.6‐900.0). Correlation, with clinical functional status, the histopathological thymus alterations and the different therapeutics used did not disclose any statistically significant differences.