Cytoproteic CSF findings in 33 MS patients: usefulness for diagnosis | Zendy

Pereira S. | Zendy; Sá M. José | Zendy; Vieira Sara | Zendy; Silva C. A. | Zendy

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Cytoproteic CSF findings in 33 MS patients: usefulness for diagnosis

Author(s) -

Pereira S.,

Sá M. José,

Vieira Sara,

Silva C. A.

Publication year - 1989

Publication title -

acta neurologica scandinavica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.967

H-Index - 95

eISSN - 1600-0404

pISSN - 0001-6314

DOI - 10.1111/j.1600-0404.1989.tb03732.x

Subject(s) - multiple sclerosis , medicine , pathology , agarose gel electrophoresis , immunology , biology , biochemistry , gene

— Although multiple sclerosis (MS) is mainly defined on clinical grounds, CSF parameters still remain important diagnostic and scoring tools. To demonstrate the usefulness of some easy laboratory techniques, a CSF cytomorphological and agarose gel electrophoresis (AGE) evaluation was undertaken in 33 MS patients: 79% presented a lymphoid cell profile and in 73% the gamma globulin fraction was abnormal. In the great majority of cases (97%) either or both cytological and electrophoretical abnormalities were found.

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