Premium
Alpha‐naphthyl‐acetate‐esterase activity in cerebrospinal fluid cells
Author(s) -
Reuck J.,
Vanderdonckt P.
Publication year - 1988
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1988.tb03644.x
Subject(s) - cerebrospinal fluid , subacute sclerosing panencephalitis , histiocyte , pathology , stain , multiple sclerosis , staining , meningitis , central nervous system , viral meningitis , medicine , chemistry , immunology , bacterial meningitis , surgery , measles , measles virus , vaccination
‐ Mono‐histiocytes and T‐lymphocytes were assessed by the cytochemi‐cal alpha‐naphthyl‐acetate‐esterase (ANAE) stain in 50 CSF samples of patients with various neurological diseases. The ANAE‐activity of lymphocytes was decreased in multiple sclerosis and subacute sclerosing panencephalitis, while the activity of mono‐histiocytes was increased in the group of infarctions and bacterial and viral infections of the central nervous system. In bacterial meningitis and viral meningo‐encephalo‐radiculitis the number of ANAE‐positive lymphocytes increased after treatment and clinical improvement. ANAE staining appears to be a useful additional tool in CSF cytology in these conditions.