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IgM binding to sialosyllactosaminylparagloboside in a patient with polyradiculoneuropathy due to Mycoplasma pneumoniae infection
Author(s) -
Inuzuka T.,
Miyatani N.,
Baba H.,
Tanaka M.,
Tanaka K.,
Sato S.,
Nakamura K.,
Miyatake T.
Publication year - 1988
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1988.tb03619.x
Subject(s) - polyradiculoneuropathy , mycoplasma pneumoniae , pathogenesis , ganglioside , antibody , medicine , immunostaining , immunology , mycoplasmataceae , pathology , guillain barre syndrome , mycoplasma , mollicutes , microbiology and biotechnology , immunohistochemistry , biology , pneumonia , biochemistry
‐ IgM in serum without paraprotein in a patient with polyradiculoneuropathy due to a Mycoplasma pneumoniae infection reacted specifically with a ganglioside, sialosyllactosaminylparagroboside (SLPG), in a human peripheral nerve on a thin‐layer chromatogram plate by an immunostaining technique. This finding suggests the possibility that anti‐SLPG antibody in the patient's serum may play a role in the pathogenesis of neuropathy.