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Narcolepsy/cataplexy. IV: Diagnostic value of daytime nap recordings
Author(s) -
Kales A.,
Bixler E. O.,
Soldatos C. R.,
Cadieux R. J.,
Manfredi R.,
VelaBueno A.
Publication year - 1987
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1987.tb07924.x
Subject(s) - nap , narcolepsy , multiple sleep latency test , sleep (system call) , cataplexy , wakefulness , psychology , sleep onset , audiology , excessive daytime sleepiness , polysomnography , medicine , anesthesia , electroencephalography , sleep disorder , modafinil , neuroscience , psychiatry , insomnia , computer science , operating system
— Sleep and wakefulness patterns in daytime naps of 50 patients with narcolepsy/cataplexy were compared with those of 50 controls. Each subject was monitored polygraphically during 2 one‐hour nap periods. A sleep‐onset REM period in either of the 2 daytime naps was observed to have a higher diagnostic sensitivity (78%) than an abnormally shortened sleep latency (68%). However, the specificities of a sleep‐onset REM period (88%) of abnormally shortened sleep latency (90%) were quite similar. When the occurrence of either a sleep‐onset REM period or a shortened sleep latency was evaluated in either of the two naps, the overall sensitivity was increased to 84% while the specificity was decreased only to 80%. The limitations of and indications for the use of testing for sleep and REM latencies in the diagnosis of narcolepsy in clinical practice are discussed.