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Localized outbreak of enteroviral meningitis in adults
Author(s) -
Kinnunen E.,
Hovi T.,
Stenvik M.,
Hellström O.,
Porras J.,
Kleemola M.,
Kantanen ML
Publication year - 1987
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1987.tb05457.x
Subject(s) - echovirus , aseptic meningitis , enterovirus , etiology , outbreak , virology , meningitis , medicine , throat , coxsackievirus , virus , viral meningitis , serotype , immunology , pathology , pediatrics , bacterial meningitis , surgery
During a thorough surveillance of viral infections of the central nervous system an outbreak of aseptic meningitis was discovered in the western part of Finland in late 1985. The 21 diseased young adults were carefully studied by different virological methods. A presumed viral etiology, in all cases of enteroviral origin, was found in 16 of 20 (80%) with adequate specimens. Four different enteroviruses were associated with this episode; in 9 cases the presumed etiological agent was echovirus 5, while coxsackie B5, echo 25 and echo 17 viruses appeared to be responsible for 4, 2 and 1 case, respectively. Sensitivity of different diagnostic methods as regards detection of the echovirus 5 infections was in order: increase of type‐specific neutralizing serum antibodies, isolation of virus from faeces, isolation from throat and group diagnosis by demonstrdling an increase in complement‐fixing antibodies to coxsackie BS virus antigen.