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Linoleic acid levels in white blood cells, platelets, and serum of multiple sclerosis patients
Author(s) -
Fisher M.,
Johnson M. H.,
Natale A. M.,
Levine P. H.
Publication year - 1987
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1987.tb03574.x
Subject(s) - linoleic acid , platelet , pathogenesis , medicine , endocrinology , multiple sclerosis , chemistry , biochemistry , immunology , fatty acid
We found a small but statistically significant reduction in the linoleic acid concentration of white blood cells and platelets in MS patients. The percent linoleic acid concentration (mean ± S.D.) in the white blood cells of 24 MS patients was 8.8 ± 1.8% as compared with 11.4 ± 4.9 in 24 age and sex‐matched controls ( p < 0.05). Platelet levels were 8.5 ± 2.4% and 10.6 ± 3.8% respectively ( P < 0.05). Serum linoleic acid levels were not significantly different in the two groups. The possible role of linoleic acid in the pathogenesis of MS has yet to be defined.