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Plasma exchange in myasthenia gravis: effect on anti‐AChR antibodies and other autoantibodies
Author(s) -
Thorlacius S.,
Lefvert A. K.,
Aarli J. A.,
Gilhus N. E.,
Halvorsen K.,
Hofstad H.,
Matre R.,
Tönder O.
Publication year - 1986
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1986.tb07875.x
Subject(s) - myasthenia gravis , acetylcholine receptor , autoantibody , antibody , endocrinology , medicine , chemistry , immunology , receptor
— Plasma exchange (PE) was performed in 6 patients with myasthenia gravis (MG). Acetylcholine receptor (AChR) antibodies and other MG‐correlated antibodies were quantified each day before, during and after PE. The antibody concentrations decreased during PE with a consisting increase between two exchanges. Repeated PE induced a transient decline in the AChR antibody concentration. The clinical improvement was maximal during the week after PE and correlated in time with increasing concentrations of AChR antibodies.