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Isolated angiitis of the central nervous system
Author(s) -
Launes J.,
Livanainen M.,
Erkinjuntti T.,
Vuorialho M.
Publication year - 1986
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1986.tb04635.x
Subject(s) - medicine , central nervous system , etiology , cyclophosphamide , vasculitis , disease , pathology , chemotherapy
Two adults with isolated angitis of the central nervous system (CNS) are described and the diagnostic criteria of the disease are evaluted. The diagnosis was based on carotid angiogram showing segmental narrowing (a “beaded” appearance) with or without microaneurysms or arterial obstruction, and on clinical observations excluding other underlying diseases. The clinical picture consisted of progressing or fluctuating symptoms and signs of CNS origin. Although the primary etiology of this rare condition remains unknown, treatment with corticosteroids and cyclophosphamide is rewarding. Thus, isolated angiitis of the CNS is treatable, contrary to some earlier assumptions. Therefore, the early diagnosis of isolated angiitis of the CNS is emphasized.