Premium
Cerebral vasculitis as presenting symptom of systemic lupus erythematosus
Author(s) -
Sanders E.A.C.M.,
Hogenhuis L.A.H.
Publication year - 1986
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1986.tb04630.x
Subject(s) - medicine , encephalomalacia , hemiparesis , vasculitis , prednisone , cerebral vasculitis , systemic disease , connective tissue disease , presentation (obstetrics) , systemic lupus erythematosus , lupus erythematosus , dermatology , angiography , surgery , pathology , disease , autoimmune disease , immunology , antibody
A 42‐year‐old woman developed right‐sided hemiparesis due to left‐sided encephalomalacia revealed by CT scan. Subsequent angiography revealed vasculitis of several intra‐cranial arteries. The ESR was 65 mm/h. Further laboratory tests revealed no evidenec of systemic disease so that no causal diagnosis could be posed. Treatment with prednisone (3 × 30 mg daily) led to complete cure of the hemiparesis within 6 weeks. Sixteen months later, the patient developed cutaneaus lesions in the neck. Histological examination of these lesions indicated the presence of systemic lupus erythematosus (SLE). Neurological presentation of SLE is exceptional, while cerebral vasculitis as initial symptom of SLE has never been described before.