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The C3‐F gene in patients with intracranial saccular aneurysms
Author(s) -
Østergaard J.R.,
BruunPetersen G.,
Kristensen B.Ø.
Publication year - 1986
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1986.tb03525.x
Subject(s) - saccular aneurysm , aneurysm , medicine , gene , risk factor , cardiology , gastroenterology , surgery , biology , genetics
The C3‐F gene has previously been found associated with atherosclerotic vascular diseases. The occurrence of the C3‐F gene was therefore investigated in a group of 110 hospitalized patients with intracranial saccular aneurysms. The C3‐F gene occurred equally often in patients and controls. In patients with a ruptured aneurysm, however, the C3‐F gene frequency was significantly increased in subjects aged 40–49 years followed by a marked and statistically significant decline with increasing age. The findings suggest that the C3‐F gene may be a risk factor for early aneurysm rupture.