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The cerebrospinal fluid in myasthenia gravis
Author(s) -
Thorlacius Sigurdur,
Aarli Johan A.
Publication year - 1985
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1985.tb00896.x
Subject(s) - cerebrospinal fluid , albumin , myasthenia gravis , csf albumin , medicine , serum albumin , pathological , endocrinology , immunology
– We examined the number of leucocytes and the concentration of total protein, albumin and IgG in the cerebrospinal fluid (CSF) from 46 patients with myasthenia gravis (MG) and 50 controls. Mean leucocyte number in the MG patients was 1634 cells/ml (controls 1244), mean total protein 0.38 g/l (controls 0.32), mean IgG 0.034 g/l (controls 0.025) and mean albumin 0.199 g/l (controls 0.176). No evidence of intrathecal IgG synthesis was demonstrated. The CSF was normal in most cases. When pathological changes occurred they were slight and could be attributed to associated diseases or to iatrogenic blood contamination of the CSF. We demonstrated that an artificial blood contamination of the CSF, although macroscopically undetectable, increased the CSF albumin concentration and the CSF albumin/serum albumin ratio considerably.