Premium
Serum potassium exercise test in the diagnosis of familial periodic paralysis
Author(s) -
Tarssanen Leo T.,
Kantola Llkka M.,
Huikko Markku E.
Publication year - 1983
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1983.tb04811.x
Subject(s) - potassium , medicine , endocrinology , paralysis , anesthesia , chemistry , surgery , organic chemistry
We studied the serum potassium rise during a 30‐min 100 W exercise test in 5 controls, 3 familial periodic paralysis (FPP) patients and their 2 symptom‐less brothers. The controls showed a steep and high exercise response (the 10‐min rise was 0.59 ± 0.13 mmol/l and the maximal rise was 0.71 ± 0.11 mmol/l). The FPP patients showed a slow and flat exercise response (the 10‐mm rise was 0.08 ± 0.11 mmol/l and the maximal rise was 0.17 ± 0.12 mmol/l, P < 0.001 for both values). The 2 symptom‐less brothers showed a similar divergence. The values of 0.05 mmol/l (10‐min) and 0.25 mmol/l (maximal) of one brother suggest the diagnosis of FPP, whereas the values of 0.55 (10‐min) and 0.65 mmol/l (maximal) of the other brother suggest the exclusion of the disease. We regard the serum potassium exercise test to be worthy of further study as a diagnostic test of FPP.