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Antibodies to nuclear and smooth muscle antigens in multiple sclerosis and control patients
Author(s) -
Hyypiä T.,
Viander M.,
Reunanen M.,
Salmi A.
Publication year - 1982
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1982.tb03116.x
Subject(s) - autoantibody , anti nuclear antibody , antibody , multiple sclerosis , radioimmunoassay , extractable nuclear antigens , medicine , antigen , immunology , pathology
Serum and CSF specimens of 30 MS patients and 30 age‐ and sex‐matched control patients with other neurological diseases were tested for autoantibodies. Indirect immunofluorescense was used to detect smooth muscle antibodies and antinuclear antibodies in the serum. Antibodies against DNA and RNA in the serum and CSF were tested by solid phase radioimmunoassays. No significant differences in autoantibody levels were found between MS and control patients.