Premium
Blood‐brain barrier integrity in patients with cerebral infarction investigated by computed tomography and serum‐CSF‐albumin
Author(s) -
AlKassab Suad,
Olsen Tom Skyhøj,
Skriver Elisabeth Bech
Publication year - 1981
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1981.tb04421.x
Subject(s) - albumin , medicine , cerebrospinal fluid , cerebral infarction , blood–brain barrier , serum albumin , lumbar puncture , computed tomography , csf albumin , lumbar , stroke (engine) , infarction , pathology , radiology , central nervous system , ischemia , myocardial infarction , mechanical engineering , engineering
Measurements of CSF‐albumin, and S/CSF‐albumin in two groups of patients with small and large infarcts failed to show BBB damage to albumin in about one half of the patients. No significant difference was found between the two groups of patients in regard to the above‐mentioned parameters. The localization of the infarcts (close to the CSF or deep in the brain) did not influence the S/CSF‐albumin. No correlation was found between the S/CSF‐albumin and the time interval between the onset of the stroke and the lumbar puncture within 96 h. Some suggestions are put forward to explain the discrepancies between the CT‐scan and S/CSF‐albumin in the assessment of BBB damage.