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Propranolol (Inderal) and clonidine (Catapressan) in the prophylactic treatment of migraine
Author(s) -
Kåss Børre,
Nestvold Knut
Publication year - 1980
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1980.tb01504.x
Subject(s) - clonidine , propranolol , medicine , nausea , anesthesia , migraine , crossover study , significant difference , alternative medicine , pathology , placebo
Twenty‐one patients continued a double‐blind crossover study to compare the prophylactic effect on migraine of propranolol and clonidine. The daily dosage of propranolol and clonidine was 160 mg and 100 μg, respectively. Statistical analysis did not show any significant difference between the two drugs in respect to headache or nausea. The number of sickleave days and the use of symptomatic drugs were both less on propranolol treatment than on clonidine, but there was no statistically conclusive difference.