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Evaluation of cerebral infarctions of the carotid area by an intravenous 133 Xenon and 99m Technetium method
Author(s) -
Tolonen U.,
Ahonen A.,
Kallanranta T.,
Hokkanen E.,
Koskinen M.,
Kuikka J.
Publication year - 1980
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1980.tb01476.x
Subject(s) - infarction , medicine , diaschisis , cerebral infarction , cerebral blood flow , lesion , significant difference , hemodynamics , internal carotid artery , carotid arteries , anesthesia , cardiology , nuclear medicine , radiology , surgery , ischemia , myocardial infarction , cerebellum
Quantitative determinations of regional cerebral blood flow (rCBF f , rCBF m ) and volume (rCBV), transfer time (rCTT) and fast compartmental weight (W f ) were performed in 34 patients with infarctions of the carotid area by a 133 Xe and 99m Tc intravenous injection method. The results were compared with clinical signs and electroencephalographic (EEG) findings. A significant difference was found between the lesion side and the control side in all the parameters except rCBV. This difference increased with the severity of the infarction and age of the patients. The difference between the two sides was especially great in the patients with totally occluded internal carotid artery. A slight diaschisis could be observed in the present infarction group. An almost significant reduction on the “normal side” was seen in W f . In order to assess the reciprocal influence of all the different blood flow parameters, the difference index (DI) √ɛ i Δ 2 i was calculated, where Δ i = the difference between the two sides in one parameter expressed in percent. This proved to be abnormal in 80% of the patients. The atraumatic isotope technique employed offers a good opportunity for the quantitative evaluation of hemodynamics in cerebral infarction and serves as an aid in the diagnosis of infarction.