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Juvenile amyotrophic lateral sclerosis
Author(s) -
Myllylä V. V.,
Toivakka E.,
AlaHurula V.,
Hokkanen E.,
EmerykSzajewska B.
Publication year - 1979
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1979.tb02965.x
Subject(s) - amyotrophic lateral sclerosis , juvenile , pediatrics , disease , medicine , population , biology , genetics , environmental health
This paper presents two juvenile cases of familial amyotrophic lateral sclerosis. They are the first and fourth child in a family with seven children from the eastern part of Finland. All seven children, as well as the parents, were examined by our group. In the first case the disease showed a rather mild course, while in the second a noticeable progression was observed even during a period of 10 months. The patients come from a rural area with a stable population and low immigration, which may favor an enrichment of certain genes and therefore support the possible hereditary basis for the disease.