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Measles‐adherent lymphocyte phenomenon of Levy in multiple sclerosis: Normal reactivity of blood lymphocytes
Author(s) -
Kinnman Jörgen,
Link Hans
Publication year - 1979
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1979.tb02934.x
Subject(s) - multiple sclerosis , measles , immunology , measles virus , lymphocyte , medicine , virology , hela , peripheral blood , cell , biology , vaccination , genetics
The measles‐adherent phenomenon described by Levy in multiple sclerosis was investigated by studying the rosetting effect of blood lymphocytes from multiple sclerosis patients and healthy controls on chronically measles infected heteroploid Hela cells (Lu 106). No significant difference in rosetting was observed, irrespective if a lymphocyte/virus infected Lu cell ratio of 10/1 or 50/1 was used. Therefore, the test is not discriminative for multiple sclerosis.