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Capillary permeability in ALS, determined through transcapillary escape rate of 125 I‐albumin
Author(s) -
Conradi S.,
Kaijser L.,
Ronnevi L.O.
Publication year - 1978
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1978.tb05873.x
Subject(s) - albumin , vascular permeability , chemistry , permeability (electromagnetism) , capillary action , medicine , biochemistry , physics , thermodynamics , membrane
Since various macromolecules have experimentally been demonstrated to be taken up by the motor end‐plates and subsequently transported through retrograde axoplasmic flow, noxious substances may gain entrance to the lower motorneurons through the same route. Consequently, the function of the capillary barrier in skeletal muscle is of interest in diseases of the lower motorneurons. the transcapillary escape rate of 125 I‐albumin was determined in six ALS patients. the values fell within the range earlier reported for normals.