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Hypokalaemic periodic paralysis and cardiomyopathy
Author(s) -
Schipperheyn J. J.,
Buruma O. J. S.,
Voogd P. J.
Publication year - 1978
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1978.tb02902.x
Subject(s) - medicine , paralysis , muscular dystrophy , weakness , cardiomyopathy , muscle weakness , limb girdle muscular dystrophy , periodic paralysis , proximal muscle weakness , cardiology , pediatrics , physical medicine and rehabilitation , physical therapy , surgery , mutation , muscle biopsy , heart failure , biopsy , biology , biochemistry , gene
The results are reported of cardiological examinations, including echocardiography, in nine members of a family suffering from hypokalaemic periodic paralysis, associated with permanent muscular weakness. The studies were performed in periods between attacks of paralysis. The slowly progressive permanent muscular weakness which is found in most of the patients with hypokalaemic periodic paralysis resembles a limb‐girdle type dystrophy. Involvement of cardiac muscle is not uncommon in patients with limb‐girdle dystrophy. Using a combination of echocardiography and ECG examination, nowadays the most sensitive screening method for the detection of cardiomyopathy, no evidence was obtained for cardiac involvement in hypokalaemic periodic paralysis patients with permanent muscular weakness.