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Clinical picture of multiple sclerosis with late onset
Author(s) -
Cazzullo C. L.,
Ghezzi A.,
Marforio S.,
Caputo D.
Publication year - 1978
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1978.tb02878.x
Subject(s) - multiple sclerosis , age of onset , medicine , pediatrics , expanded disability status scale , psychiatry , disease
A group of 47 patients (multiple sclerosis (M.S.) diagnosed according to Schumacher's criteria) with age at onset over 40 years, was studied by statistical analysis and compared with a control group (100 M.S. patients with onset between ages 18 and 38). The following features appear peculiar in this group: – the most frequent initial symptoms are motor disturbances – the onset is generally monosymptomatic – the course is generally progressive and more severe than that of controls, as seen by Kurtzke's Disability Scale, relapse rate, interval between first and second attack – the course is more severe when the onset is progressive and characterized by motor disturbances.