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THE EFFECT OF INTRAARTERIAL ADMINISTERED AMINOPHYLLINE ON CEREBRAL HEMODYNAMICS IN MAN
Author(s) -
Magnussen Ib,
HøedtRasmussen Kaj
Publication year - 1977
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1977.tb05633.x
Subject(s) - aminophylline , vasoconstriction , hemodynamics , anesthesia , medicine , cerebral blood flow
The dose‐effect relationship of intracarotid administered aminophylline on cerebral hemodynamics in man was investigated by means of an intraarterial 133 Xenon injection method. A dose dependent vasoconstriction was clearly demonstrated. The maximum efficacy expressed as mcasured decreased in global cerebral blood flow was 21.9 per cent ± 6.2 SD. Administration of as little as 1 mg aminophylline produced a measureable vasoconstriction.