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THE VIBRATION PERCEPTION THRESHOLD IN GASTRECTOMIZED PATIENTS WITH LOW SERUM B 12
Author(s) -
Roos Dorthe
Publication year - 1977
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1977.tb01460.x
Subject(s) - audiology , medicine , perception , gastrectomy , psychology , neuroscience , cancer
In 42 gastrectomized patients with low serum B 12 the vibration perception threshold (VPT) was significantly elevated as compared with a control group. Forty patients were followed up after 6–12 months of intensive vitamin B 12 therapy. Within an adequately treated group (25 patients) remission of symptoms and signs of peripheral neuropathy was observed, including a statistically significant reduction of the VPT measured on the medial malleolus and big toe. Such a reduction was not observed in the adequately treated group of patients with myelopathy. Findings in the inadequately treated group were less definite, both as regards remission of clinical findings and VPT. In four untreated patients the neurological symptoms and signs progressed during the follow‐up period. On the basis of these findings intensive and long‐lasting treatment with vitamin B 12 is recommended for gastrectomized patients showing signs of neuropathy.