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SPINAL TUMOURS ASSOCIATED WITH INCREASED INTRACRANIAL PRESSURE
Author(s) -
Børgesen Svend Erik,
Sørensen Søren Claus,
Olesen Jes,
Gjerris Flemming
Publication year - 1977
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1977.tb01432.x
Subject(s) - cerebrospinal fluid , pathophysiology , intracranial pressure , medicine , cerebrospinal fluid pressure , lumbar , outflow , pathology , anesthesia , surgery , physics , meteorology
Two cases of increased intracranial pressure associated with lumbar intraspinal tumours are reported. On the basis of protein investigations and constant flow infusion manometric tests, the pathophysiology of the increased intracranial pressure is discussed. It is demonstrated that protein macromolecules leak from the tumour into the cerebrospinal fluid and suggested that these are responsible for mechanical obstruction of the outflow channels for the cerebrospinal fluid.