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REPRESENTATION of CUTANEOUS AFFERENTS BY FLUORIDE‐RESISTANT ACID PHOSPHATASE (FRAP)‐ACTIVE TERMINALS IN the RAT SUBSTANTIA GELATINOSA ROLANDI
Author(s) -
Knyihár Elizabeth,
Csillik Bertalan
Publication year - 1976
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1976.tb04340.x
Subject(s) - denervation , sciatic nerve , spinal cord , chemistry , acid phosphatase , hindlimb , gating , anatomy , neuroscience , medicine , psychology , enzyme , biochemistry
While transection of the sciatic nerve results in a complete ipsilateral extinction of FRAP activity in respective segments of the rat spinal cord, cutaneous denervation of the hind leg induces a patchy disappearance of this same enzyme in the Rolando substance. the possible participation of FRAP in metabolism of the primary sensory transmitter substance, its relation to substance P and its involvement in gating mechanisms are discussed.