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GENETIC FACTORS IN TEMPORAL LOBE EPILEPSY
Author(s) -
Jensen Inge
Publication year - 1975
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1975.tb05833.x
Subject(s) - epilepsy , temporal lobe , genetic predisposition , psychiatry , family history , medicine , pediatrics , surgery , disease
Genetic investigation of 74 patients with temporal lobe epilepsy, resistant to medication, who underwent unilateral temporal lobectomy 1960‐1969. Thirty per cent had a positive family history of epilepsy; 49 per cent of other neurological diseases; and 46 per cent of major psychiatric disorders. Neither of the genetic factors per se influenced the therapeutic result or the psychiatric status at follow‐up. A multiple epileptic or neurological predisposition affecting first degree relatives unfavourably influenced the prognosis regarding relief from seizures. A multiple psychiatric predisposition in parents and/or siblings unfavourably influenced the psychiatric status.