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STATISTICAL CORRELATIONS OF DIFFUSE CEREBRAL ATROPHY, WITH SPECIAL REFERENCE TO DIAGNOSTIC AND AETIOLOGIAL CLUES
Author(s) -
Iivanainen Matti
Publication year - 1975
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1975.tb01376.x
Subject(s) - atrophy , cerebral atrophy , pathology , medicine , psychology , neuroscience
To evaluate diagnostic and aetiological clues for diffuse cerebral atrophy, the statistical correlations between 35 pneumoencephalographic and 97 clinical variables in 268 patients were analysed. Each case of diffuse cerebral atrophy was originally of unknown cause, and all had pneumoencephalography. Ventricular diffuse atrophy correlated positively with psychic and co‐ordinative impairment and dysarthria, and cortical diffuse cerebral atrophy with psychic impairment ( P < 0.01 to 0.001). There was a close correlation ( P < 0.001) of cortical diffuse cerebral atrophy with use of vibrating tools at work. Psychic impairment combined with co‐ordinative dysfunction and dysarthria is an unspecific syndrome, but should make one think of diffuse cerebral atrophy. Arteriosclerosis, abuse of alcohol, and vibrating tools at work appear to have aetiological significance for some types of diffuse cerebral atrophy. Thus the number of patients with idiopathic diffuse cerebral atrophy may rapidly decline.