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EFFECTS OF L‐DOPA AND L‐TRYPTOPHAN ON THE CEREBRAL BLOOD FLOW IN THE DOG
Author(s) -
EkströmJodal Barbro,
Essen Claes von,
Hauggendal Egil,
Roos BjörnErik
Publication year - 1974
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1974.tb01342.x
Subject(s) - cerebral blood flow , tryptophan , blood flow , anesthesia , medicine , cerebral circulation , chemistry , biochemistry , amino acid
The effect of L‐DOPA and L‐tryptophan on the cerebral blood flow was studied in anaesthetized dogs injected intravenously with one or other of the drugs. Cerebral blood flow was measured with the radio‐active gas elimination technique with external γ‐registration. After L‐DOPA there were signs of an increase of the cerebral blood flow followed later by a decrease. The effect of L‐tryptophan on the cerebral blood flow in all experiments was a decrease.