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CRANIAL AND SPINAL COMPONENTS OF THE CEREBROSPINAL FLUID PRESSURE‐VOLUME CURVE
Author(s) -
Löfgren Jan,
Zwetnow Nicolaus N.
Publication year - 1973
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1973.tb01331.x
Subject(s) - cerebrospinal fluid , intracranial pressure , volume (thermodynamics) , cistern , medicine , anatomy , anesthesia , pathology , physics , thermodynamics , history , archaeology
A quantitative analysis of the contributions of the cranial and spinal compartments to the cerebrospinal fluid pressure‐volume curve was made using dogs. The curve was determined by rapid continuous injection of fluid into the cisterna magna with simultaneous measurement of the pressure. Spinal block at the C 1 level was produced by inflation of an epidural rubber balloon allowing the recording of the pressure‐volume curve for the isolated cranial system. By subtraction of the two curves obtained, the spinal pressure‐volume curve could be calculated. 70 % of the variation in volume within the system was related to the spinal section and 30 % to the cranial section. The intracranial curve represents the effects on the fluid pressure of forced alterations in the volume of the intracranial vascular bed. The spinal compartment has a quantitatively defined and probably mechanically important function as an expansion vessel for the intracranial system.