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JUVENILE CEREBRAL ARTERIOSCLEROSIS AND OTHER CEREBRAL ARTERIOPATHIES OF CHILDHOOD—SIX AUTOPSIED CASES
Author(s) -
Harvey Frederick H.,
Alvord Ellsworth C.
Publication year - 1972
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1972.tb07569.x
Subject(s) - medicine , arteriosclerosis , cerebral arteries , thrombosis , cerebral infarction , cerebral arteriosclerosis , pathology , cardiology , pediatrics , ischemia
Six autopsied cases of rare cerebrovascular diseases of childhood have been presented, including arteriosclerosis, alternating hemiparesis (“moyamoya” syndrome), phyototic aneurysm caused by an awn of grass, arterio‐occlusive infarct occurring near the time of birth, necrotizing arteritis predominantly affecting the nervous system and infantile thrombosis with cerebral infarction associated with tuberous sclerosis. These cases have raised some important but difficult questions with regard to the pathogenesis of strokes during childhood as compared to adulthood, especially whether cerebral arteriosclerosis is a response to diverse injuries during childhood and young adulthood, and whether there is a factor which protects the cerebral arteries during infancy and childhood such that the systemic arteries bear the brunt of vascular disease as compared to adulthood. In addition, a reasonable classification of cerebral arterial diseases during childhood (based on tissue diagnoses) is presented and discussed.