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THE CYTOLOGY OF THE NORMAL CEREBROSPINAL FLUID
Author(s) -
Sörnäs Rune
Publication year - 1972
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1972.tb07553.x
Subject(s) - cerebrospinal fluid , cytology , peripheral blood mononuclear cell , pathology , medicine , differential diagnosis , reference range , mean value , cell , nuclear medicine , chemistry , in vitro , mathematics , biochemistry , statistics
With a sedimentation method for routine cytological examination of the CSF, 38 patients without known neurological or physical disease were studied. The method allows a reliable differential cell count, that is, it represents the true distribution of the cells in the CSF. The investigation showed that the mean value of the total cell count was 1.45 mononuclear cells per cmm. The counts ranged from 0.3 to 6.2 mononuclears per cmm. It was also found that CSF normally contains mainly lymphocytes, median 86.5 % with a range from 99 % to 63 %, and monocytoids, median 10.5 % with a range from 28 % to 0 %, but also macrophages, median 2 % ranging from 9 % to 0 %. Neither in the total cell count nor in the differential cell count were polynuclear cells found.