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NERVE CONDUCTION STUDIES IN CHARCOT—MARIE—TOOTH DISEASE
Author(s) -
Humberstone P. M.
Publication year - 1972
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1972.tb07539.x
Subject(s) - tooth disease , medicine , nerve conduction , nerve conduction velocity , sensory nerve , motor nerve , disease , nerve conduction study , sensory system , anatomy , neuroscience , pathology , psychology
Earlier studies of nerve conduction in Charcot‐Marie‐Tooth Disease have produced contradictory results, therefore a further study has been undertaken attempting to establish the pattern of nerve conduction abnormalities that may be anticipated. Standard methods of measuring nerve conduction have been employed in twenty‐three patients with undoubted Charcot‐Marie‐Tooth disease. Motor nerve conduction was always abnormal in the legs, and usually abnormal in the arms; sensory nerve conduction was always abnormal in the arms. Abnormal motor conduction was usually associated with clinical wasting but sensory nerve conduction abnormalities occurred in the absence of clinical sensory loss in most patients. The severity of the nerve conduction impairment appeared to be directly related to the duration of the disease, and possibly to the clinical severity of the disease.