Premium
FOLIC ACID AND THE HALF‐LIFE OF DIPHENYLHYDANTOIN IN MAN
Author(s) -
Andreasen P. Buch,
Hansen J. Mølholm,
Skovsted L.,
SiersbækNielsen K.
Publication year - 1971
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1971.tb07469.x
Subject(s) - folic acid , metabolism , medicine , chemistry , pharmacology , endocrinology
The half‐life of diphenylhydantoin in man was investigated before and after treatment with high doses of folic acid and no significant changes were found. It thus seems unlikely that the possible influence of folic acid on diphenylhydantoin metabolism is mediated by an increased liver metabolism; the possibility, however, remains that the pattern of diphenylhydantoin‐metabolites are altered.