Premium
CEREBROSPINAL FLUID OXYGEN TENSION IN MAN DURING HALOTHANE ANAESTHESIA AND HYPERVENTILATION
Author(s) -
Harmsen P.,
Bay J.
Publication year - 1970
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1111/j.1600-0404.1970.tb05812.x
Subject(s) - hyperventilation , anesthesia , oxygen tension , halothane , cerebrospinal fluid , arterial oxygen tension , oxygen , nitrous oxide , medicine , lumbar puncture , lumbar , chemistry , surgery , organic chemistry
Oxygen tension in lumbar cerebrospinal fluid was monitored during halothane‐N 2 O anaesthesia in 6 patients undergoing craniotomy. Beckman's oxygen‐micro electrode was used. Results showed (1) a rise in oxygen tension during the beginning of the anaesthesia which is largely ascribed to an increase in cerebral blood flow induced by the anaesthetic, (2) a fall in oxygen tension during 30 minutes of hyper‐ventilation where arterial CO 2 tension decreased to 20 mm Hg, (3) a minimum oxygen tension measured during hyperventilation which is within the limits of normal CSF oxygen tension reported by others. It is argued that lumbar CSF oxygen tension may represent an average tissue oxygen tension of the central nervous system.