Open AccessStem cell differentiation and expansion for clinical applications of tissue engineering
Author(s) -
Guillot Pascale V.,
Cui Wei,
Fisk Nicholas M.,
Polak Dame Julia
Publication year - 2007
Publication title -
journal of cellular and molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.44
H-Index - 130
eISSN - 1582-4934
pISSN - 1582-1838
DOI - 10.1111/j.1582-4934.2007.00106.x
Subject(s) - tissue engineering , bench to bedside , stem cell biology , stem cell , computer science , medicine , biomedical engineering , biology , medical physics , microbiology and biotechnology , embryo , reproductive technology , embryogenesis
• Introduction • The essentials of tissue engineering ‐ Biomaterials ‐ Cell types for tissue engineering ‐ Stem cells ‐ Embryonic stem cells ‐ ‘Adult’ stem cells ‐ Transition from bench to bedside ‐ Cell expansion/microencapsulation• ConclusionsAbstract This invited review discusses the latest advances stem cell biology, tissue engineering and the transition from bench to bedside. An overview is presented as to which the best cell source might be for cell therapy and tissue engineering applications, best biomaterials currently available and the challenges the field faces to translate basic research into therapies for a large number of human diseases.