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Reducing the pathogenicity of B m NPV in silkworms using silver nanoparticles
Author(s) -
Ruyi Zou,
Zhenyou Zou,
Miao Liu,
Ninan Chen,
Shuoqi Xu,
Aiping Ma,
Lianwei Zhou,
Tianle Qian,
Yiqing Zhou,
Cui Wang,
Bing Hu,
Zhongyuan Shen,
Ruobing Liang,
Zhenlin Yang,
Jinhua Xia,
Liming Hong
Publication year - 2012
Publication title -
entomologia experimentalis et applicata
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.765
H-Index - 83
eISSN - 1570-7458
pISSN - 0013-8703
DOI - 10.1111/j.1570-7458.2012.01302.x
Subject(s) - pathogenicity , biology , silver nanoparticle , virus , virology , capsid , in vivo , microbiology and biotechnology , nanoparticle , materials science , nanotechnology
This study examined the efficacy of silver nanoparticles colloid ( Ag NPC ) in reducing the pathogenicity of the B ombyx mori L . ( L epidoptera: B ombycidae) nuclear polyhydrosis virus ( B m NPV ) in silkworms. We found that the survival rate of the infected silkworms improved significantly, from 22 to 67%, following treatment with Ag NPC . However, Ag NP s caused clumping of hemocytes in vivo and this was associated with slight weight loss and reduced cocoon size in the treated silkworms. The adherence of silver nanoparticles to the virus or hemocytes caused them to aggregate. In addition, by catalyzing the generation of free radicals, silver nanoparticles can perforate and break up the virus capsids, proteins, and DNA of the B m NPV s, thus restraining their pathogenicity and improving the survival capacity of infected silkworms.