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THE GENETIC ARCHITECTURE OF GROWTH RATE IN JUVENILE TAKIFUGU SPECIES
Author(s) -
Hosoya Sho,
Kai Wataru,
Fujita Masashi,
Miyaki Kadoo,
Suetake Hiroaki,
Suzuki Yuzuru,
Kikuchi Kiyoshi
Publication year - 2013
Publication title -
evolution
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.84
H-Index - 199
eISSN - 1558-5646
pISSN - 0014-3820
DOI - 10.1111/j.1558-5646.2012.01781.x
Subject(s) - biology , juvenile , zoology , genetic architecture , takifugu rubripes , fishery , evolutionary biology , ecology , fish <actinopterygii> , genetics , gene , phenotype
Closely related species have often evolved dramatic differences in body size. Takifugu rubripes (fugu) is a large marine pufferfish whose genome has been sequenced, whereas T. niphobles is the smallest species among Takifugu . We show that, unsurprisingly, the juvenile growth rate of T. rubripes is higher than that of T. niphobles in a laboratory setting. We produced F 2 progenies of their F 1 hybrids and found one quantitative trait locus (QTL) significantly associated with variation in juvenile body size. This QTL region (3.5 Mb) contains no known genes directly related to growth phenotype (such as IGF s) except Fgf21 , which inhibits growth hormone signaling in mouse. The QTL in Takifugu spp. is distinct from the region previously known to control body size variations in stickleback or tilapia. Our results suggest that in the fish tested herein, genomic regions underlying body size evolution might have different genetic origins. They also suggest that many diverse traits in Takifugu spp. are amenable to genetic mapping.