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Y‐haplotype Screening of Local Patrilineages Followed by Autosomal STR Typing Can Detect Likely Perpetrators in Some Populations
Author(s) -
Huang Daixin,
Shi Shaoxing,
Zhu Chuanhong,
Yi Shaohua,
Ma Wei,
Wang Haisheng,
Li Huamin
Publication year - 2011
Publication title -
journal of forensic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.715
H-Index - 96
eISSN - 1556-4029
pISSN - 0022-1198
DOI - 10.1111/j.1556-4029.2011.01830.x
Subject(s) - haplotype , pedigree chart , typing , y str , microsatellite , genetics , biology , genotype , gene , allele
The male‐specific, human Y‐chromosomal short tandem repeats (Y‐STRs) are very useful in forensic analysis and human evolution studies. The authors report two sexual crime cases in which the perpetrators were successfully traced using Y‐haplotype screening of local patrilineages followed by autosomal STR typing. First, several main local patrilineages from local cases were investigated using Y‐STR haplotyping, aimed to find the pedigrees whose haplotypes were identical or similar to those of the crime scene samples. Then, several key suspects were defined from the screened pedigrees, and autosomal STR typing was performed to identify the perpetrator of the crime. The application of Y‐haplotype screening of local patrilineages followed by autosomal STR typing in these two cases demonstrates its usefulness for solving sexually related crimes in certain populations.