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DETECHIP ® : A Sensor for Drugs of Abuse *
Author(s) -
Burks Raychelle M.,
Pacquette Shari E.,
Guericke Mike A.,
Wilson Mark V.,
Symonsbergen David J.,
Lucas Kerry A.,
Holmes Andrea E.
Publication year - 2010
Publication title -
journal of forensic sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.715
H-Index - 96
eISSN - 1556-4029
pISSN - 0022-1198
DOI - 10.1111/j.1556-4029.2010.01323.x
Subject(s) - drugs of abuse , analyte , suspect , characterization (materials science) , identification (biology) , fluorescence , computer science , chemistry , chromatography , nanotechnology , materials science , medicine , pharmacology , psychology , drug , biology , optics , physics , botany , criminology
The design and preliminary characterization of a novel sensor for drugs of abuse, DETECHIP ® , is described in this proof‐of‐concept note. Combining both colorimetric and fluorimetric assays, DETECHIP ® is suitable for lab and field use. More than a conventional spot test which provides a single “yes or no” answer, DETECHIP ® provides twenty responses for a more complete characterization of suspect material. This is accomplished by visually noting colorimetric and fluorescent changes of carefully selected dyes upon the addition of test analytes, including drugs of abuse, with respect to controls. Color and fluorescence changes are recorded numerically so that a 20 digit identification code can be constructed for comparison of test analytes and known compounds. DETECHIP ® is applicable to a variety of drugs, both plant‐derived and synthetic, addressing the need to use several different spot tests simultaneously for a single sample.