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Radiological Correlate of Ocular Flutter in a Case with Paraneoplastic Encephalitis
Author(s) -
Newey Christopher R.,
Sarwal Aarti,
Wu Guiyun
Publication year - 2013
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2011.00659.x
Subject(s) - medicine , magnetic resonance imaging , positron emission tomography , hyperintensity , ataxia , paraneoplastic cerebellar degeneration , pathology , nuclear medicine , radiology , antibody , psychiatry , immunology , autoantibody
We present an interesting [ 18 F]fluoro‐2‐deoxyglucose positron emission tomography (FDG‐PET) imaging finding in a patient with ocular flutter and cerebellar ataxia as part of anti‐Ma 1/2 antibody‐mediated paraneoplastic syndrome associated with a testicular seminoma. He had a typical anterior mesial temporal hyperintensity on magnetic resonance imaging (MRI) without gadolinium enhancement. In addition, his FDG‐PET images showed increased deep cerebellar and inferior rectus and superior oblique ocular muscles FDG uptake. This case is the first to visualize in vivo the possible underlying neuropathological mechanism of ocular flutter associated with cerebellar nuclei on functional imaging.