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Flow Velocity of the Superior Sagittal Sinus Is Reduced in Patients with Idiopathic Normal Pressure Hydrocephalus
Author(s) -
Kuriyama Nagato,
Tokuda Takahiko,
Yamada Kei,
Akazawa Kentaro,
Hosoda Makoto,
Sakai Koji,
Watanabe Yoshiyuki,
Nakagawa Masanori
Publication year - 2011
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2011.00592.x
Subject(s) - medicine , superior sagittal sinus , hydrocephalus , sagittal plane , sinus (botany) , anatomy , surgery , botany , thrombosis , biology , genus
BACKGROUND The pathogenesis and diagnostic methods for idiopathic normal pressure hydrocephalus (iNPH) have been active areas of research in recent years. This study was performed to determine whether there is a venous return abnormality in the intracranial circulation of patients with iNPH. METHODS The subjects were 20 patients with iNPH (Group N) and 24 normal controls (Group C). MR venography (MRV) was performed at the superior sagittal sinus 2 cm above the confluence of the sinuses, and the flow velocities were compared between Groups N and C. RESULTS During normal breathing, the maximum velocities were significantly lower in Group N (18.8 cm/second) than in Group C (22.9 cm/second; ( P < .01). During the Valsalva maneuver, compared to normal breathing, the velocity decreased in both groups, but both the maximum (Max V) and minimum (Min V) velocities were significantly lower in Group N than in Group C ( P < .01). CONCLUSIONS The flow velocity at the superior sagittal sinus was lower and the flow velocity during the Valsalva maneuver decreased more in patients with iNPH than in controls. The results may reflect the presence of abnormal intracranial venous flow in iNPH. J Neuroimaging 2011;21:365‐369.