Premium
Brainstem Involvement in Sjögren's Syndrome‐Related Sensory Neuronopathy
Author(s) -
Damasceno Alfredo,
França Jr. Marcondes C.,
Zanardi Verônica A.,
Nucci Anamarli
Publication year - 2010
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2009.00393.x
Subject(s) - medicine , brainstem , corneal reflex , sensory system , magnetic resonance imaging , reflex , lesion , dorsal root ganglion , pathology , neuroscience , anatomy , dorsum , radiology , anesthesia , psychology
BACKGROUND AND PURPOSE Sensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Magnetic resonance imaging (MRI) studies have shown abnormalities limited to T2‐weighted high signal intensity in the posterior columns.METHODS AND RESULTS A 65‐year‐old woman with Sjögren syndrome had slowly progressive unsteadiness of gait and limb paresthesias. A blink reflex examination suggested a paramedian brainstem lesion, confirmed by MRI.CONCLUSIONS Sjögren's syndrome‐related SN may be associated with a more diffuse immune‐mediated aggression, involving also the brainstem, and leading to some of the blink reflex abnormalities observed in nonparaneoplastic SN.