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Pituitary Adenomas Can Appear as Hypermetabolic Lesions in 18 F‐FDG PET Imaging
Author(s) -
Ryu Stephen I.,
Tafti Bashir A.,
Skirboll Stephen L.
Publication year - 2010
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2008.00347.x
Subject(s) - medicine , positron emission tomography , pet imaging , pituitary adenoma , nuclear medicine , adenoma , pathology , radiology
OBJECTIVE The 2‐deoxy‐2‐[ 18 F] fluoro‐D‐glucose positron emission tomography (FDG‐PET) scan is commonly used in detection and staging of many malignant neoplasms. However, several benign or non‐neoplastic conditions avidly accumulate 18 F‐FDG, causing ambiguity in interpretation of results. It is unknown whether pituitary adenomas uptake 18 F‐FDG and appear positive in PET imaging. Here, we present 2 cases of benign pituitary adenoma with elevated metabolic activity in 18 F‐FDG PET scan.METHODS Medical, neurologic, and psychiatric histories; physical examination findings; laboratory work up results; and pathologic and imaging studies were documented.RESULTS The 18 F‐FDG‐PET images revealed foci of marked FDG uptake in pituitary adenomas of 2 patients.CONCLUSION Pituitary micro‐ and macro‐adenomas may present as hypermetabolic foci on 18 F‐FDG PET scan.