Premium
Early Contrast‐Enhanced Magnetic Resonance Imaging with Fluid‐Attenuated Inversion Recovery in Multiple Sclerosis
Author(s) -
Kataoka Hiroshi,
Taoka Toshiaki,
Ueno Satoshi
Publication year - 2009
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2008.00315.x
Subject(s) - fluid attenuated inversion recovery , medicine , multiple sclerosis , magnetic resonance imaging , contrast (vision) , nuclear medicine , radiology , white matter , gadolinium , contrast enhancement , materials science , artificial intelligence , psychiatry , computer science , metallurgy
OBJECTIVE Contrast‐enhanced magnetic resonance imaging (MRI) with fluid‐attenuated inversion recovery (contrast FLAIR) is particularly useful for the detection of meningeal lesions. However, whether contrast FLAIR is useful in multiple sclerosis (MS) remains uncertain. This study evaluated the usefulness of contrast FLAIR in MS.PATIENTS AND METHODS We prospectively studied the clinical histories and brain MRI studies of 6 patients with clinically definite MS diagnosed according to the new McDonald criteria. Contrast FLAIR (repetition time [TR] 9,000 ms; echo time [TE] 120 ms; inversion time [TI] 2,200 ms; 5‐mm slice thickness, with a 1‐mm interslice gap) was obtained with the use of a bolus of gadolinium diethylenetriamine pentaacetic acid.RESULTS Three enhancing plaques located in the periventricular or juxtacortical areas showed higher intensity on contrast FLAIR than on other MR sequences. In contrast, 8 enhancing plaques in the deep white matter or infratentorial areas showed no increased signals on contrast FLAIR.CONCLUSION Our findings suggest that early contrast‐enhanced imaging with FLAIR may be helpful for the further detection of MS plaques, particularly those located in periventricular and juxtacortical lesions.