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Extensive Brainstem Ischemia on Neuroimaging Does Not Preclude Meaningful Recovery from Locked‐In Syndrome: Two Cases of Endovascularly Managed Basilar Thrombosis
Author(s) -
Tomycz Nestor D.,
Holm Margo B.,
Horowitz Michael B.,
Wechsler Lawrence R.,
Raina Ketki,
Gupta Rishi,
Jovin Tudor G.
Publication year - 2008
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2007.00147.x
Subject(s) - medicine , basilar artery , thrombolysis , locked in syndrome , ischemia , thrombosis , neuroimaging , brainstem , stroke (engine) , radiology , surgery , anesthesia , cardiology , mechanical engineering , psychiatry , myocardial infarction , engineering
We report 2 patients with angiographically demonstrated basilar artery thrombosis who received emergent intra‐arterial thrombolysis with successful recanalization of the basilar artery. In the ensuing weeks after the procedure, both patients were in a locked‐in state and had sustained large bilateral regions of pontine ischemia on brain imaging. Following aggressive supportive care and rehabilitation, outcomes obtained prospectively revealed that both patients made a remarkable recovery, becoming fully independent with Barthel scores of 20 and modified Rankin scores of 2.