Premium
MR Findings of Intrathecal Chemotherapy‐Related Myelopathy in Two Cases: Mimicker of Subacute Combined Degeneration
Author(s) -
Lu ChiaHung,
Yao Ming,
Liu HonMan,
Chen YaFang
Publication year - 2007
Publication title -
journal of neuroimaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.822
H-Index - 64
eISSN - 1552-6569
pISSN - 1051-2284
DOI - 10.1111/j.1552-6569.2007.00094.x
Subject(s) - medicine , subacute combined degeneration , conus medullaris , myelopathy , spinal cord , magnetic resonance imaging , hyperintensity , spinal cord diseases , weakness , radiology , pathology , surgery , psychiatry
We report the findings of spinal magnetic resonance imaging (MRI) in 2 patients who had undergone intrathecal chemotherapy and presented with the subacute onset of ascending numbness and weakness. MRI revealed a symmetric hyperintensity at the posterior columns of the spinal cord from the lower cervical region down to the conus medullaris level on T2‐weighted images, and no abnormal enhancement. The imaging findings are similar to those seen in subacute combined degeneration (SCD), but the serum vitamin B 12 levels were normal in these 2 cases.